Tablet Compaction Simulator Demonstration At CMAC

Huxley Bertram – CMAC Open Day At the University of Strathclyde

The annual CMAC event gave the Huxley Bertram powder compaction team, the opportunity to demonstrate the Tablet Compaction Simulator based at CMAC and meet those involved in the field of material characterisation, drug discovery, and research and development.

CMAC offered visitors to the event a laboratory tour, which included an overview of the capabilities of Huxley Bertram’s servo hydraulic tablet press simulator.  Demonstrated by Martin Bennett, one of Huxley Bertram’s leading experts in the field of Powder Compaction machines and instrumentation.

Martin Bennett, Senior Engineer said: “It was great to meet people in person again. CMAC has very impressive facilities and it is a bonus to have the most advanced compaction simulator in Europe sited there.”

Huxley Bertram looks forward to attending the CMAC event in 2023.

 

HB50 Servo Hydraulic Tablet Compaction-Simulator for Powder Compaction Analysis

CMAC Open Day, Showcasing Tablet Compaction Simulation

CMAC Open Day – 16th to 18th May 2022

This year’s live CMAC Open Day will be held between, 16th and 18th May 2022 at CMAC’s Technology & Innovation Centre in Scotland.  CMAC is the world-leading centre for medicines manufacturing research, skills technology, and translation.

As a CMAC industry partner, Huxley Bertram will be showcasing its Tablet Compaction Simulator range. Delegates who sign up for CMAC’s open day and laboratory tours will be offered a live demonstration of the Huxley Bertram HB50, the high-speed, automated tablet press simulator.

Come and speak with one of our team about how we can support your drug discovery program and reduce time to market; learn more about the full range of Tablet Compaction Simulators offered, including OEB5 containment options, and the extensive tooling and accessories available, such as the adhesion punch, heated tooling, and tri-axial decompression options.

Register Here for this exciting event.

Huxley Bertram Showcase STEM Careers with Cambridge LaunchPad

Huxley Bertram proudly supports the Cambridge LaunchPad Initiative

Cambridge LaunchPad is a movement led by science and technology companies that invest their talent and resources to show that STEM is for all, and to inspire young people into STEM careers.

As an industry partner of Cambridge LaunchPad, three of Huxley Bertram’s Junior Engineers engaged with 260 Year 10 students in Cambridgeshire over two days, sharing their knowledge and enthusiasm for engineering. The sessions were delivered through the format of collaborative classroom experiments and live online sessions. Providing real-world engineering examples.

Based on a Huxley Bertram design, the engineers developed an interesting classroom experiment, to mimic a test rig for shock absorption and penetration testing of safety hardhats, through a drop test from height.

Using everyday household items such as playdoh, a rolling pin, golf ball, and a ruler, students measured the drop effect from multiple heights to the playdoh billet.  The results were plotted in a graph to prove the theory that drop height influences kinetic energy and force.  The students responded enthusiastically, commenting “I like doing DT and I might do engineering now” and “I really like it because it wasn’t like doing normal physics.”

Steve Hales Business Director for Huxley Bertram said: “It has been great for Huxley Bertram to work with Form the Future.  We are immensely proud of our engineering team in both developing and delivering the Cambridge LaunchPad sessions, helping to inspire Year 10 pupils, and highlighting the career opportunities available in an engineering environment.”

Lisa Taylor, Cambridge LaunchPad Programme Manager, said: “Thank you to the Huxley Bertram team for delivering engaging content and sessions to our students, providing real-life interactive engineering examples, that will inspire future generations into STEM careers.”

In addition to supporting Cambridge LaunchPad, Huxley Bertram also welcomes applications for Year 10 work placements and student internships for 2023.

Huxley Bertram Shipping Another HB100 – with Containment, Tablet Compaction Simulator

Another Huxley Bertram Tablet Compaction Simulator is shipping from our Waterbeach, Cambridge, UK facility in December 2021.
The Tablet Compaction Simulator shown incorporates a fully validated containment system. The system accommodates up to OEB5 dependent upon the transfer level used. Rapid transfer parts, continuous liners or pass through / VBE arrangements can be provided.
The unit also includes a novel vacuum cyclone system to recover up to 98% of any powder collected during cleaning cycles.

If you would like more information please get in touch with us at – info@huxleybertram.com

 

 

 

WHITE PAPER – Fast and Non-Destructive Prediction of Tablet Dissolution by Terahertz Spectroscopy

Details of the paper published jointly by Huxley Bertram, University of Cambridge, University of Strathclyde, EPSRC, CMAC, and Teraview.

TeraSolve – Terahertz Spectroscopy Tool Collaboratively Developed by Huxley Bertram

Huxley Bertram is proud to be involved in collaboratively developing new and leading technology, TeraSolve, it uses terahertz spectroscopy to measure the total porosity of tablets.
Together with TeraView (https://teraview.com/), Axel Zeitler from University of Cambridge (https://www.ceb.cam.ac.uk/) and Daniel Markl from the University of Strathclyde, Huxley Bertram has developed a completely new terahertz spectroscopy sensor that can be used for at-line measurements for the development and quality testing of immediate release tablets in the pharmaceutical industry.
The instrument is capable of measuring the total porosity of tablets without any sample preparation in transmission in less than a second. The results of the measurement can be monitored in real-time and stored for subsequent analysis such as chemometric analysis using commonly available tools such as SIPAT.
Further research is in progress to translate this technology into in-line and/or on-line sensing applications for the pharmaceutical industry. The TeraSolve was developed as part of a collaborative project with GSK funded by Innovate UK, project reference 104196.
For more information, contact us at info@huxleybertram.com

Compaction Simulation Forum US June 2019

There were over 70 attendees at the Compaction Simulator Forum in the US. Martin Bennett and Jean Le Floch attended for Huxley Bertram. Adhesion was one of the key topics at the forum.

 

Compaction Simulation Forum US June 2019

We are pleased to announce that Huxley Bertram is once again sponsoring the Compaction Simulator Forum in the US. It  takes place 04-05 June 2019 in New Brunswick, New Jersey – more details here.

Compaction Simulation Forum Europe Report

The eighth Compaction Simulation Forum (CSF2018-EU) was held at University of Cambridge 17- 19 September 2018. Sponsored by Huxley Bertram, the Forum gathered 60 attendees from the UK, Europe and the USA. Sixteen universities from eight countries were represented, as well as eight pharmaceutical companies and ten equipment/services vendors. Leading UK companies such as GSK, Pfizer, BMS and Johnson Matthey were in attendance. The scientific programme included keynote addresses, podium presentations, flash presentations and posters. Martin Bennett, Huxley Bertram’s compaction expert, presented on the important effects of rotary tablet press elasticity.

Once again the CSF reflected a growing interest in numerical simulation as a companion to experimental simulation. Other important trends displayed at the event included:

  • Terahertz-based porosity assessment of pharmaceutical tablet
  • Continuous tablet production
  • The importance of servo-hydraulic compaction simulators in the field of tableting research.

Two similar events are in the planning process for 2019.

(Photographs courtesy of Department of Chemical Engineering and Biotechnology, University of Cambridge, and Daniel Markl, University of Strathclyde.)